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Weekly Chest CasesArchive of Old Cases

Case No : 707 Date 2011-05-17

  • Courtesy of Hwan-Seok Yong, Eun-Young Kang. / Korea University Guro Hospital
  • Age/Sex 19 / M
  • Chief ComplaintChronic cough and sputum.
  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4

Figure 1

Diagnosis With Brief Discussion

Diagnosis
Kartagener syndrome (primary ciliary dyskinesia, immotile ciliary syndrome)
Radiologic Findings
Chest CT images show bronchiectasis in right lingular segment and LML and bronchiolitis in RLL. Stomach gas is seen in the right side suggesting situs inversus. PNS view reveals sinusitis showing haziness in both maxillary sinuses.
Brief Review
Kartagener syndrome is a chronic lung disease that occurs when cilia are unable to move. Kartagener syndrome is a rare genetic birth defect. Individuals with Kartagener syndrome have abnormal or absent ciliary motion. Kartagener syndrome is also called Primary Ciliary Dyskinesia, and Immotile Cilia Syndrome, Afzelius syndrome, Kartagener triad, Zivert syndrome, and Zivert-Kartagener triad. Cilia are tiny hair-like structures that are present on the surfaces of many different types of cells. One of the functions of cilia is to move mucus out of the respiratory passages. During infections, more mucus is produced and because the abnormal cilia can't move or move ineffectively, mucus becomes stuck and blocks the respiratory tract, causing various complications. Some common symptoms of Kartagener syndrome are chronic rhinitis, recurrent or chronic sinusitis, recurrent or chronic bronchitis, bronchiectasis, olfactory impairment, and infertility. Treatment is aimed at reducing symptoms and slowing disease progression. Complications of Kartagener syndrome include bronchiectasis, difficulty breasthing, and chronic wheezing and coughing. Bronchiectasis occurs when the bronchial tubes are blocked and chronically infected, causing the tubes to weaken and stretch out. The widened tubes allow more mucus and bacteria to accumulate, leading to infection and possibly pneumonia.
References
1. Nadel HR, Stringer DA, Turner JA, Sturgess JM. The immotile cilia syndrome: radiological manifestations. Radiology. 1985;154:651-5.
2. High-Resolution CT of patients with primary ciliary dyskinesia. AJR. 2007;188:1232-8.
Keywords
lung, congenital,

No. of Applicants : 138

▶ Correct Answer : 123/138,  89.1%
  • - Yokohama-asahi-chuo-general hospital , Japan Kyoko Nagai
  • - Assam Medical college , India samudra borah
  • - Okayama University , Japan Akihiro Tada
  • - China Medical University , China zhang wei
  • - Severance hospital , Korea (South) Saerom Hong
  • - Yonsei University College of Medicine, Shinchon Severance hospital , Korea (South) Young Joo Suh
  • - Youngdong Hospital , Korea (South) Sang Min Lee
  • - Okayama university, Department of Pathology , Japan Junya Itakura
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  • - clinique de SAVOIE , France, Metropolitan gay-depassier philippe
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  • - A.P.Chest hospital , India k bhaskar
  • - Yonsei university Shinchon Severance hospital , Korea (South) Na-young Shin
  • - Deptt of Radiodiagnosis & Imaging, PGIMER chandigarh , India Ram Galwa
  • - Radnet Teleradiology , Turkey Murat Ulusoy
  • - SMC , Korea (South) Yi Kyung Kim
  • - Teleradiology solutions , India harish bhambore
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  • - PingTung Christian Hospital ,China Medical University ,Taiwan,R.O.C. , Taiwan Jun Jun Yeh
  • - jaslok hospital & research centre mumbai , India JAINENDRA JAIN
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  • - , Korea (South) Yoo Na Kim
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  • - Medical College Chest Hospital,Thrissur,Kerala , India Raveendran TK
  • - Das Allgemeine Krankenhaus Celle , Germany Davis Chiramel
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  • - radiologist, aditya imaging centre , India vivek patel
  • - Dongnam Institute of Radiological and Medical Sciences , Korea (South) Dae Wook Yeh
  • - Az Osp Santa Maria Terni , Italy angelo carloni
  • - Inha University Hospital , Korea (South) Ju Won Lee
  • - IRSA La Rochelle France , France Denis Chabassiere
  • - AMRITA INSTITUTE OF MEDICAL SCIENCES , India sivasubramanian srinivasan
  • - DrRP GMEDICAL COLLEGE TANDA , India DINESH SOOD
  • - IRSA Rochefort , France Viviane Pages
  • - SAISEIKAI KURIHASHI HOSPITAL , Japan YASUO OOKUBO
  • - University of British Columbia , Canada Amr Ajlan
  • - Radiologie Brabois adultes , France ROPION helene
  • - Chung-Nam National University Hospital , Korea (South) KI-TAE HAN
  • - Hopital Louis Pradel Lyon , France Clement Proust
  • - Kizawa memorial Hospital , Japan Yo Kaneko
  • - McGill University Health Center , Canada Alexandre Semionov
  • - McGill , Canada ilan azuelos
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  • - UWO , Canada S Lee
  • - Homs National Hospital , Syria Rami Abou Zalaf
  • - Toyama University Hospital, Laboratory of Pathology , Japan TOMONORI TANAKA
  • - RNT Medical College, Udaipur , India madhu singhal
  • - CHRU lille , France manuel toledano
  • - RNT Medical College,Udaipur , India Amit Gupta
  • - University of Rochester Medical Center , United States Hongju Son
  • - Chonnam National University Hospital , Korea (South) Daun Lee
  • - Institute of Chest Diseases Calicut , India Dr.Divya Nair
  • - Saint Malo , France jean-baptiste Noel
  • - All India Institute of Medical Sciences , India Ashish Gupta
  • - Onomichi municipal hospital , Japan Hirofumi Mifune
  • - Severance hospital , Korea (South) MINA PARK
  • - Suncheon Plus radiology , Korea (South) Park Sang Hyun
  • - Korea univ. hospital, radiology department , Korea (South) Choo jiyung
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  • - yeong gwang general hospital , Korea (South) Mokhee Kim
  • - Brabois - CHU Nancy , France Alban Gervaise
  • - CHA Bundang hospital , Korea (South) Hyerin Kim
  • - Kasturba Medical College , India Chandan Kakkar
  • - Armed Forces Yangju Hospital , Korea (South) Ho-Joon Lee
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  • - Vitalife Clinics , Pune , India. , India Rahul Deshmukh
  • - MBAL Sliven , Bulgaria Zlatina Boneva
  • - Fukuyama daiichi Hospital , Japan Mototsugu Saeki
  • - Chonbuk National University Hospital , Korea (South) Jisoo Song
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  • - Kohka Public Hospital , Japan Akitoshi Inoue
  • - Severance hospital , Korea (South) Hyunjoo Shin
  • - Onomichi Municipal Hospital , Japan Takuro Fushimi
  • - Shree Diagnostics , India amol jagdale
  • - IRSA , France jean-luc BIGOT
  • - Louisiana State University - Shreveport , United States Carlos Previgliano
  • - Kyungpook university hospital , Korea (South) Yoo Jin Lee
  • - Ewha Womans University Hospital , Korea (South) YOOKYUNG KIM
  • - Mallinckrodt Institute of Radiology , United States Naganathan Mani
  • - Iwate Medical University , Japan Akio Akahane
  • - Chungnam National University hospital, Korea , Korea (South) sunkyoung you
  • - o2 clinic, pudukottai, india , India siva raja
  • - Himeji Red Cross Hospital , Japan ryota inai
  • - NMC hospital Dubai , United Arab Emirates vickrant malhotra
  • - Bupyong Serim Hospital , Korea (South) Hee Seok Choi
  • - Mackay Memorial Hospital, Taipei , Taiwan Sheng-Yeh Shen
  • - Hotel-Dieu Montreal , Canada nicolas gautier
  • - korea university , Korea (South) kyungeun lim
  • - GSVM Medical college Kanpur , India Shashank Sood
  • - McGill University , Canada Sean Carr
  • - Pneumologia Universitaria, Policlinico di Bari , Italy Mario Damiani
  • - IRCCS Istituto Oncologico - Bari , Italy Carlo Florio
  • - Zaid Alsheriti hospital- Alsweida , Syria jehad alakabani
  • - Okayama university , Japan Mayu Uka
  • - NASA SCANS , India RAKESH BHATIA
  • - Vital Imaging Centre, Mumbai,India , India Ganesh Agrawal
  • - Beaulieu clinic Geneva , Switzerland gilles GENIN
  • - Virgin Mary Hospital Burgas , Bulgaria VLADISLAV RUSINOV
  • - Chonnam university hospital , Korea (South) LEE JI HYUN
  • - Istanbul , Turkey Armagan Sarac
  • - Hospital Sotiria, Athens, Greece , Greece Vasilios Tzilas
  • - UZ GASTHUISBERG , Belgium Johan COOLEN
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